Article

Novel data-driven subtypes and stages of brain atrophy in the ALS-FTD spectrum

2023-08-10

Abstract excerpt

<title>Abstract</title> <p>Background TDP-43 proteinopathies represents a spectrum of neurological disorders, anchored clinically on either end by amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD). The ALS-FTD spectrum exhibits a diverse range of clinical presentations with overlapping phenotypes, highlighting its heterogeneity. This study aimed to use disease progression modeling to iden...

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Literature Corpus work: abfade04-8381-5387-b5ce-a7187e4ba0b8
DOI: 10.21203/rs.3.rs-3183113/v1

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