Article
Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration.
JAMA neurology - 1 Sept 2016
Ranasinghe Kamalini G, Rankin Katherine P, Pressman Peter S, Perry David C, Lobach Iryna V, Seeley William W, Coppola Giovanni, Karydas Anna M, Grinberg Lea T, Shany-Ur Tal, Lee Suzee E, Rabinovici Gil D, Rosen Howard J, Gorno-Tempini Maria Luisa, Boxer Adam L, Miller Zachary A, Chiong Winston, DeMay Mary, Kramer Joel H, Possin Katherine L, Sturm Virginia E, Bettcher Brianne M, Neylan Michael, Zackey Diana D, Nguyen Lauren A, Ketelle Robin, Block Nikolas, Wu Teresa Q, Dallich Alison, Russek Natanya, Caplan Alyssa, Geschwind Daniel H, Vossel Keith A, Miller Bruce L
Abstract excerpt
IMPORTANCE: Clearer delineation of the phenotypic heterogeneity within behavioral variant frontotemporal dementia (bvFTD) will help uncover underlying biological mechanisms and improve clinicians' ability to predict disease course and to design targeted management strategies. OBJECTIVE: To identify subtypes of bvFTD syndrome based on distinctive patterns of atrophy defined by selective vulnerability of specific...
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