Article

Functional network collapse in neurodegenerative disease

2023-12-04

Abstract excerpt

Cognitive and behavioral deficits in Alzheimer’s disease (AD) and frontotemporal dementia (FTD) result from brain atrophy and altered functional connectivity. However, it is unclear how atrophy relates to functional connectivity disruptions across dementia subtypes and stages. We addressed this question using structural and functional MRI from 221 patients with AD (n=82), behavioral variant FTD (n=41), corticobasa...

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Literature Corpus work: aea4bb39-a823-5c8a-92dc-b11e44255ae0
DOI: 10.1101/2023.12.01.569654

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