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Article

Patterns of gray matter atrophy in genetic frontotemporal dementia: results from the GENFI study.

Neurobiology of aging - 1 Feb 2018

Cash David M, Bocchetta Martina, Thomas David L, Dick Katrina M, van Swieten John C, Borroni Barbara, Galimberti Daniela, Masellis Mario, Tartaglia Maria Carmela, Rowe James B, Graff Caroline, Tagliavini Fabrizio, Frisoni Giovanni B, Laforce Robert, Finger Elizabeth, de Mendonça Alexandre, Sorbi Sandro, Rossor Martin N, Ourselin Sebastien, Rohrer Jonathan D

Abstract excerpt

Frontotemporal dementia (FTD) is a highly heritable condition with multiple genetic causes. In this study, similarities and differences of gray matter (GM) atrophy patterns were assessed among 3 common forms of genetic FTD (mutations in C9orf72, GRN, and MAPT). Participants from the Genetic FTD Initiative (GENFI) cohort with a suitable volumetric T1 magnetic resonance imaging scan were included (319): 144...

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Identifiers

PMID: 29172163
DOI: 10.1016/j.neurobiolaging.2017.10.008
PMCID: PMC5759893

Genes

GRN
MAPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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