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Article

Amplifying and ameliorating light avoidance in mice with photoreceptor targeting and CGRP sensitization

2025-05-28

Abstract excerpt

<h4>Objective</h4> To determine the photoreceptor basis of light avoidance in mice and assess the effect of CGRP sensitization on this behavior. <h4>Background</h4> Prior studies have suggested that photophobia is mediated by a subset of retinal ganglion cells (RGCs) that contain melanopsin, making them intrinsically photosensitive (ipRGCs). These cells also receive extrinsic input from cones, which can also med...

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Literature Corpus work
2f5d5c64-19e2-5dd5-8e98-3b4374b4d15c
DOI
10.1101/2025.05.24.655946
Open publication

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Amplifying and ameliorating light avoidance in mice with photoreceptor targeting and CGRP sensitizationDOI 10.1101/2025.05.24.655946
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