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Article

Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells.

Scientific reports - 6 Dec 2021

Sheng Yanghui, Chen Lujing, Ren Xiaozhi, Jiang Zheng, Yau King-Wai

Abstract excerpt

Intrinsically-photosensitive retinal ganglion cells (ipRGCs) are non-rod/non-cone retinal photoreceptors expressing the visual pigment, melanopsin, to detect ambient irradiance for various non-image-forming visual functions. The M1-subtype, amongst the best studied, mediates primarily circadian photoentrainment and pupillary light reflex. Their intrinsic light responses are more prolonged than those of rods and...

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Identifiers

PMID: 34873237
DOI: 10.1038/s41598-021-02832-9
PMCID: PMC8648817

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