Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of circadian clock gene mutations on nonvisual photoreception in the mouse.

Investigative ophthalmology & visual science - 25 Jan 2012

Owens Leah, Buhr Ethan, Tu Daniel C, Lamprecht Tamara L, Lee Janet, Van Gelder Russell N

Abstract excerpt

PURPOSE: Mice lacking rods and cones retain pupillary light reflexes that are mediated by intrinsically photosensitive retinal ganglion cells (ipRGCs). Melanopsin is necessary and sufficient for this nonvisual photoreception. The mammalian inner retina also expresses the potential blue light photopigments cryptochromes 1 and 2. Previous studies have shown that outer retinal degenerate mice lacking cryptochromes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circadian Clocks
Share to Circadian Rhythm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cryptochromes

Share to Mice, Inbred C3H

Share to Photic Stimulation

Share to Retinal Degeneration

Share to Retinal Ganglion Cells

Share to Vision, Ocular

Source

Open in PubMed Open full text

Identifiers

PMID: 22159024
DOI: 10.1167/iovs.11-8717
PMCID: PMC3292377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of circadian clock gene mutations on nonvisual photoreception in the mouse.PMID 22159024Read ↗

Identifying the photoreceptive inputs to the mammalian circadian system using transgenic and retinally degenerate mice.Semantic proximity Read ↗

Inner retinal photoreception independent of the visual retinoid cycle.Semantic proximity Read ↗

Nonvisual light responses in the Rpe65 knockout mouse: rod loss restores sensitivity to the melanopsin system.Semantic proximity Read ↗

Characterization of an ocular photopigment capable of driving pupillary constriction in mice.Semantic proximity Read ↗

Four of the six Drosophila rhodopsin-expressing photoreceptors can mediate circadian entrainment in low light.Semantic proximity Read ↗

Reduced pupillary light responses in mice lacking cryptochromes.Semantic proximity Read ↗

Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses.Semantic proximity Read ↗

Contribution of the eye and of <i>opn4xa</i> function to circadian photoentrainment in the diurnal zebrafishSemantic proximity Read ↗

Visual system hyperexcitability and compromised V1 receptive field properties in early-stage retinitis pigmentosa in miceSemantic proximity Read ↗

Lack of Melanopsin Is Associated with Extreme Weight Loss in Mice upon Dietary Challenge.Semantic proximity Read ↗

Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice.Semantic proximity Read ↗

Thresholds for masking responses to light in three strains of retinally degenerate mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.