Article
Characterization of an ocular photopigment capable of driving pupillary constriction in mice.
Nature neuroscience - 1 Jun 2001
Lucas R J, Douglas R H, Foster R G
Abstract excerpt
This work demonstrates that transgenic mice lacking both rod and cone photoreceptors (rd/rd cl) retain a pupillary light reflex (PLR) that does not rely on local iris photoreceptors. These data, combined with previous reports that rodless and coneless mice show circadian and pineal responses to light, suggest that multiple non-image-forming light responses use non-rod, non-cone ocular photoreceptors in mice. An...
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