Article

FAM35A associates with REV7 and modulates DNA damage responses of normal and BRCA1-defective cells

2018-03-22

Abstract excerpt

<h4>ABSTRACT</h4> In order to exploit the specific vulnerabilities of tumors, it is urgent to identify the basis of associated defects in genome maintenance. One unsolved problem is the mechanism of inhibition of processing of DNA double-strand break repair by REV7 and its influence on DNA repair pathways. We searched for REV7-associated proteins in human cells and found FAM35A, a protein of previously unknown fu...

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Literature Corpus work: 2f598d8f-dcfd-5b4b-97fc-aabf7a1d8fe0
DOI: 10.1101/287375

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