Article

The principles of peptide selection by the transporter associated with antigen processing

2023-06-17

Abstract excerpt

The adaptive immune response eliminates infected and cancer cells through the recognition of antigenic peptides displayed by major compatibility complex class I (MHC-I) molecules 1, 2 . A single transporter, the transporter associated with antigen processing (TAP), supplies nearly the entire peptide repertoire for the many MHC-I alleles 3–5 . A fundamental unresolved question is how TAP transports peptides with...

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Literature Corpus work: 2ee94f67-eed1-5101-a408-2de1e139692f
DOI: 10.1101/2023.06.16.545308

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