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Article

Exploring the minimal functional unit of the transporter associated with antigen processing.

FEBS letters - 15 Aug 2005

Koch Joachim, Guntrum Renate, Tampé Robert

Abstract excerpt

TAP, an ABC transporter in the ER membrane, provides antigenic peptides derived from proteasomal degradation to MHC class I molecules for inspection by cytotoxic T lymphocytes at the cell surface so as to trace malignant or infected cells. To investigate the minimal number of transmembrane segments (TMs) required for assembly of the TAP complex based on hydrophobicity algorithms and alignments with other ABC...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 2

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Source

Identifiers

PMID: 16061226
DOI: 10.1016/j.febslet.2005.07.006

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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