Article

Multi-omic analysis of the cardiac cellulome defines a vascular contribution to cardiac diastolic dysfunction in obese female mice

2022-03-27

Abstract excerpt

Coronary microvascular dysfunction (CMD) is associated with cardiac dysfunction and predictive of cardiac mortality in obesity, especially in females. Emerging evidence suggests development of heart failure with preserved ejection fraction in females with CMD and that mineralocorticoid receptor (MR) antagonism may be more efficacious in obese female, versus male, HFpEF patients. Accordingly, we examined the hypoth...

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Literature Corpus work: 2ee0206d-530d-51c1-98e3-93d6714f8542
DOI: 10.1101/2022.03.24.485542

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Multi-omic analysis of the cardiac cellulome defines a vascular contribution to cardiac diastolic dysfunction in obese female miceDOI 10.1101/2022.03.24.485542Read

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