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Article

Obesity and diabetes are major risk factors for epicardial adipose tissue inflammation

20 Jul 2021

Abstract excerpt

BACKGROUNDEpicardial adipose tissue (EAT) directly overlies the myocardium, with changes in its morphology and volume associated with myriad cardiovascular and metabolic diseases. However, EAT's immune structure and cellular characterization remain incompletely described. We aimed to define the immune phenotype of EAT in humans and compare such profiles across lean, obese, and diabetic patients.METHODSWe...

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Share to Cardiovascular Disease and Adiposity
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PMID: 34283808
DOI: 10.1172/jci.insight.145495

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