Article
Identification of a pro-elongation effect of diallyl disulfide, a major organosulfur compound in garlic oil, on microglial process.
The Journal of nutritional biochemistry - 1 Apr 2020
Xu Xing, Hu Peili, Ma Yaoying, Tong Lijuan, Wang Dan, Wu Yue, Chen Zhuo, Huang Chao
Abstract excerpt
Microglia are the innate immune cells in the nervous system. In the resting state, they display a ramified morphology, while upon disease stimulation their processes would be retracted, along with pro-inflammatory cytokine overproduction. Reversing microglial process retraction may help reduce pro-inflammatory cytokine production and restore microglia's ability to scan surrounding environments, rendering brain...
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