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Article

Microglial M1/M2 polarization and metabolic states.

British journal of pharmacology - 1 Feb 2016

Orihuela Ruben, McPherson Christopher A, Harry Gaylia Jean

Abstract excerpt

Microglia are critical nervous system-specific immune cells serving as tissue-resident macrophages influencing brain development, maintenance of the neural environment, response to injury and repair. As influenced by their environment, microglia assume a diversity of phenotypes and retain the capability to shift functions to maintain tissue homeostasis. In comparison with peripheral macrophages, microglia...

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Identifiers

PMID: 25800044
DOI: 10.1111/bph.13139
PMCID: PMC4742299

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