Article

Programmed Death-Ligand 1 (PD-L1) Expression in Patients with Primary or Secondary Myelofibrosis

2023-10-09

Abstract excerpt

It has been described in mice models that Primary Myelofibrosis (PMF) with JAK2-V617F mutation has an increased expression of programmed death-ligand 1 (PD-L1) in megakaryocytes leading to cancer immune evasion by inhibiting the T-lymphocytes. To prove this hypothesis, we quantified PD-L1 expression on 29 bone marrow (BM) biopsies. We created a scoring system to quantify PD-L1 expression in megakaryocytes. We obta...

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Literature Corpus work: 2e6f77a2-c875-5455-9fae-eafbad1c3f76
DOI: 10.22541/au.169688244.48985917/v1

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