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Article

Immunoproteasome Genes Are Modulated in CD34+ JAK2V617F Mutated Cells from Primary Myelofibrosis Patients.

International journal of molecular sciences - 22 Apr 2020

Di Rosa Michelino, Giallongo Cesarina, Romano Alessandra, Tibullo Daniele, Li Volti Giovanni, Musumeci Giuseppe, Barbagallo Ignazio, Imbesi Rosa, Castrogiovanni Paola, Palumbo Giuseppe A

Abstract excerpt

Primary myelofibrosis (PMF) is a rare myeloproliferative neoplasm characterized by stem-cell-derived clonal over-proliferation of mature myeloid lineages, bone marrow fibrosis, osteosclerosis, defective erythropoiesis, and pro-inflammatory cytokine over-expression. The aim of the present study was to highlight possible differences in the transcriptome among CD34+ cells from peripheral blood (PB) of PMF patients....

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Identifiers

PMID: 32331228
DOI: 10.3390/ijms21082926
PMCID: PMC7216198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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