Article

Nutrient State, Aging, and Diet Modulate SAM50-Dependent Mitochondrial Remodeling and Systemic Metabolic Signatures

2026-02-16

Abstract excerpt

<title>Abstract</title> Although Sorting and Assembly Machinery 50 (SAM50) is known to regulate nutritional and metabolic stress related to ageing, its exact role is not well understood. This experimental study combines both human and animal models to understand the role that SAM50 plays in nutrient, age-related metabolic remodeling. We also wanted to define the clinical relevance of SAMM50 genetic variation i...

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Literature Corpus work: 2e30fe00-e658-56b2-b92e-e0a6a6c31f1c
DOI: 10.21203/rs.3.rs-8704245/v1

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