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Article

Ablation of <i>Sam50</i> is associated with fragmentation and alterations in metabolism in murine and human myotubes

2023-05-22

Abstract excerpt

The Sorting and Assembly Machinery (SAM) Complex is responsible for assembling β-barrel proteins in the mitochondrial membrane. Comprising three subunits, Sam35, Sam37, and Sam50, the SAM complex connects the inner and outer mitochondrial membranes by interacting with the mitochondrial contact site and cristae organizing system (MICOS) complex. Sam50, in particular, stabilizes the mitochondrial intermembrane space...

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Literature Corpus work
50e70e6b-a481-5a24-b91f-c2fdc4dda7ea
DOI
10.1101/2023.05.20.541602
Open publication

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Ablation of <i>Sam50</i> is associated with fragmentation and alterations in metabolism in murine and human myotubesDOI 10.1101/2023.05.20.541602
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