Article

Age-related MICOS Complex Dysregulation Impairs Mitochondrial 3D Architecture and Metabolic Homeostasis in the Liver

2024-06-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background & Aims</h4> Aging is associated with a significant decline in mitochondrial function in the liver, leading to an increased risk of liver disease. This study examines age-related changes in the mitochondrial structure of human and murine livers using a combination of Serial Block-Face Scanning Electron Microscopy (SBF-SEM) and mass spectrometry approaches. <h4>Methods</h4> This s...

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Literature Corpus work: 4228edde-e204-583a-9a3a-d3f88790b5b0
DOI: 10.1101/2024.06.20.599846

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Age-related MICOS Complex Dysregulation Impairs Mitochondrial 3D Architecture and Metabolic Homeostasis in the LiverDOI 10.1101/2024.06.20.599846Read

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