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Article

The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.

FEBS open bio - 1 Jul 2021

Li Zuyin, Shen Weixing, Wu Gang, Qin Changjiang, Zhang Yijie, Wang Yupeng, Song Guohe, Xiao Chao, Zhang Xin, Deng Guilong, Wang Ruitao, Wang Xiaoliang

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic lipid accumulation. SAMM50 encodes Sam50, a mitochondrial outer membrane protein involved in the removal of reactive oxygen species, mitochondrial morphology and regulation of mitophagy. Certain single nucleotide polymorphisms of SAMM50 have been reported to be correlated with NAFLD. However, the contribution of SAMM50 polymorphisms to the...

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Identifiers

PMID: 33728819
DOI: 10.1002/2211-5463.13146
PMCID: PMC8255833

Genes

SAMM50

Provenance

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The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.PMID 33728819Read ↗

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