Article

An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease

2019-12-06

Abstract excerpt

<h4>ABSTRACT</h4> Multivariate methods are known to increase the statistical power of association detection, but they have lacked essential follow-up analysis tools necessary for understanding the biology underlying these associations. We developed a novel computational workflow for multivariate GWAS follow-up analyses, including fine-mapping and identification of the subset of traits driving associations (driver...

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Literature Corpus work: 2e19f5c4-cf0d-5fe6-91ef-74e85e059b51
DOI: 10.1101/867267

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