Article

A Bayesian network-based framework to uncover the causal effects of genes on complex traits based on GWAS data

2022-12-27

Abstract excerpt

Deciphering the relationships between genes and complex traits could help us better understand the biological mechanisms leading to phenotypic variations and disease onset. Univariate gene-based analyses are widely used to characterize gene-phenotype relationships, but are subject to the influence of confounders. Furthermore, while some genes directly contribute to traits variations, others may exert their effects...

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Literature Corpus work: db7a7649-c259-5ffa-8238-06c44e93c145
DOI: 10.1101/2022.12.25.22283943

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