Article

TrkA abundance is increased in cutaneous nerves in bortezomib-induced neuropathy

2025-07-03

Abstract excerpt

<h4>Background and objectives</h4> Tropomyosin receptor kinase A (TrkA), a high-affinity receptor for nerve growth factor (NGF), is highly expressed in nociceptive neurons and plays a key role in nociception. Increased NGF levels have been related to local angiogenesis. This study investigates skin biopsies of multiple myeloma patients who developed peripheral neuropathy during bortezomib treatment for localizati...

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Literature Corpus work: 2de4848a-b3e5-59c7-8171-b839df580264
DOI: 10.1101/2025.07.02.25330620

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