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Article

Chemotherapy-induced peripheral neuropathy: evidence from genome-wide association studies and replication within multiple myeloma patients.

BMC cancer - 15 Aug 2018

Mahmoudpour Seyed Hamidreza, Bandapalli Obul Reddy, da Silva Filho Miguel Inácio, Campo Chiara, Hemminki Kari, Goldschmidt Hartmut, Merz Maximilian, Försti Asta

Abstract excerpt

BACKGROUND: Based on the possible shared mechanisms of chemotherapy-induced peripheral neuropathy (CIPN) for different drugs, we aimed to aggregate results of all previously published genome-wide association studies (GWAS) on CIPN, and to replicate them within a cohort of multiple myeloma (MM) patients. METHODS: Following a systematic literature search, data for CIPN associated single nucleotide polymorphisms...

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Identifiers

PMID: 30111286
DOI: 10.1186/s12885-018-4728-4
PMCID: PMC6094450

Genes

BCL6
FBXO33
INTU

Provenance

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