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Prediction of peripheral neuropathy in multiple myeloma patients receiving bortezomib and thalidomide: a genetic study based on a single nucleotide polymorphism array.

Hematological oncology - 1 Dec 2017

García-Sanz Ramón, Corchete Luis Antonio, Alcoceba Miguel, Chillon María Carmen, Jiménez Cristina, Prieto Isabel, García-Álvarez María, Puig Noemi, Rapado Immaculada, Barrio Santiago, Oriol Albert, Blanchard María Jesús, de la Rubia Javier, Martínez Rafael, Lahuerta Juan José, González Díaz Marcos, Mateos María Victoria, San Miguel Jesús Fernando, Martínez-López Joaquín, Sarasquete María Eugenia

Abstract excerpt

Bortezomib- and thalidomide-based therapies have significantly contributed to improved survival of multiple myeloma (MM) patients. However, treatment-induced peripheral neuropathy (TiPN) is a common adverse event associated with them. Risk factors for TiPN in MM patients include advanced age, prior neuropathy, and other drugs, but there are conflicting results about the role of genetics in predicting the risk of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27605156
DOI: 10.1002/hon.2337

Genes

PLCG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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