Article
Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma: a prospective analysis of data from the HOVON-65/GMMG-HD4 trial.
The Lancet. Oncology - 1 Nov 2010
Broyl Annemiek, Corthals Sophie L, Jongen Joost Lm, van der Holt Bronno, Kuiper Rowan, de Knegt Yvonne, van Duin Mark, el Jarari Laila, Bertsch Uta, Lokhorst Henk M, Durie Brian G, Goldschmidt Hartmut, Sonneveld Pieter
Abstract excerpt
BACKGROUND: Bortezomib-induced peripheral neuropathy is a dose-limiting toxicity in patients with multiple myeloma, often requiring adjustment of treatment and affecting quality of life. We investigated the molecular profiles of early-onset (within one treatment cycle) versus late-onset (after tw...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.