Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bortezomib-induced peripheral neuropathy: A genome-wide association study on multiple myeloma patients.

Hematological oncology - 1 Feb 2018

Campo Chiara, da Silva Filho Miguel Inacio, Weinhold Niels, Mahmoudpour Seyed Hamidreza, Goldschmidt Hartmut, Hemminki Kari, Merz Maximilian, Försti Asta

Abstract excerpt

The proteasome-inhibitor bortezomib was introduced into the treatment of multiple myeloma more than a decade ago. It is clinically beneficial, but peripheral neuropathy (PNP) is a side effect that may limit its use in some patients. To examine the possible genetic predisposing factors to PNP, we performed a genome-wide association study on 646 bortezomib-treated German multiple myeloma patients. Our aim was to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bortezomib
Share to CDH13 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DCC gene

Share to PNP gene

Share to Genome-Wide Association Study

Share to Peripheral Nervous System Diseases

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Identifiers

PMID: 28317148
DOI: 10.1002/hon.2391

Genes

PNP
CDH13
DCC
TENM3
THBS4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bortezomib-induced peripheral neuropathy: A genome-wide association study on multiple myeloma patients.PMID 28317148Read ↗

A Genome-Wide Association Study Identifies a Novel Locus for Bortezomib-Induced Peripheral Neuropathy in European Patients with Multiple Myeloma.Semantic proximity Read ↗

Genetic Susceptibility to Bortezomib-Induced Peripheral Neuroropathy: Replication of the Reported Candidate Susceptibility Loci.Semantic proximity Read ↗

Impact of Genetic Polymorphisms on Bortezomib-Induced Peripheral Neuropathy in Multiple Myeloma: A Systematic Review and Bioinformatics Analysis.Semantic proximity Read ↗

Genetic factors underlying the risk of bortezomib induced peripheral neuropathy in multiple myeloma patients.Semantic proximity Read ↗

Prediction of peripheral neuropathy in multiple myeloma patients receiving bortezomib and thalidomide: a genetic study based on a single nucleotide polymorphism array.Semantic proximity Read ↗

Chemotherapy-induced peripheral neuropathy: evidence from genome-wide association studies and replication within multiple myeloma patients.Semantic proximity Read ↗

A genetic variant study of bortezomib-induced peripheral neuropathy in Chinese multiple myeloma patients.Semantic proximity Read ↗

Genetic risk factors for bortezomib-induced peripheral neuropathy in an Asian population: A genome-wide association study in South KoreaSemantic proximity Read ↗

Genetic variation associated with bortezomib-induced peripheral neuropathy.Semantic proximity Read ↗

Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma: a prospective analysis of data from the HOVON-65/GMMG-HD4 trial.Semantic proximity Read ↗

Bortezomib induced peripheral neuropathy and single nucleotide polymorphisms in PKNOX1Semantic proximity Read ↗

Genetic Risk Factors for Bortezomib-induced Neuropathic Pain in an Asian Population: A Genome-wide Association Study in South Korea.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.