Article

General dimensions of human brain morphometry inferred from genome-wide association data

2021-10-25

Abstract excerpt

<h4>Background</h4> Understanding the neurodegenerative mechanisms underlying cognitive declines in the general population may facilitate early detection of adverse health outcomes in late life. This study investigates biological pathways shared between brain morphometry, ageing, and cognitive ability. <h4>Methods</h4> We develop Genomic Principal Components Analysis (genomic PCA) to model general dimensions of...

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Literature Corpus work: 2dbbb1bc-7564-5561-af6c-ebb274ee4c27
DOI: 10.1101/2021.10.22.465437

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