Article
Joint modeling of human cortical structure: Genetic correlation network and composite-trait genetic correlation.
NeuroImage - 15 Aug 2024
Shen Jiangnan, Zhang Yiliang, Zhu Zhaohan, Cheng Youshu, Cai Biao, Zhao Yize, Zhao Hongyu
Abstract excerpt
Heritability and genetic covariance/correlation quantify the marginal and shared genetic effects across traits. They offer insights on the genetic architecture of complex traits and diseases. To explore how genetic variations contribute to brain function variations, we estimated heritability and genetic correlation across cortical thickness, surface area, and volume of 33 anatomically predefined regions in left...
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