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Brain Structure and Function Show Distinct Relations With Genetic Predispositions to Mental Health and Cognition.

Biological psychiatry. Cognitive neuroscience and neuroimaging - 1 Mar 2023

Liu Shu, Smit Dirk J A, Abdellaoui Abdel, van Wingen Guido A, Verweij Karin J H

Abstract excerpt

BACKGROUND: Mental health and cognitive achievement are partly heritable, highly polygenic, and associated with brain variations in structure and function. However, the underlying neural mechanisms remain unclear. METHODS: We investigated the association between genetic predispositions to various mental health and cognitive traits and a large set of structural and functional brain measures from the UK Biobank...

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PMID: 35961582
DOI: 10.1016/j.bpsc.2022.08.003

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