Polygenic Risk Scores: The Next Step for Improved Risk Stratification in Coronary Artery Disease?

Abstract excerpt

Despite significant advances in the management of coronary artery disease (CAD) and reductions in annual mortality rates in recent decades, this disease remains the leading cause of death worldwide. Consequently, there is an ongoing need for efforts to address this situation. Current clinical algorithms to identify at-risk patients are particularly inaccurate in moderate-risk individuals. For this reason, the...

Topics

• Humans
• Coronary Artery Disease
• Genetic Risk Score
• Genetic Testing
• Genome-Wide Association Study
• Polymorphism, Single Nucleotide
• Risk Assessment