Article

METTL3 Aggravates Intimal Hyperplasia by Facilitating the m <sup>6</sup> A-YTHDC1-dependent SGK1 Gene Transcription

2025-01-09

Abstract excerpt

<h4>Background</h4> Vascular smooth muscle cell (VSMC) migration and proliferation substantially contribute to neointimal hyperplasia related to in-stent restenosis. N 6 -methyladenosine (m 6 A) catalyzed by the methyltransferase-like 3 (METTL3)-involved methyltransferase complex is the most abundant RNA epigenetic modification in eukaryotes, but the role of m 6 A RNA methylation in VSMC migration and prolifer...

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Literature Corpus work: 2d267690-d651-5b1e-8b6c-c678a20d27d8
DOI: 10.1101/2025.01.09.632275

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