Article

METTL3 drives heart failure by regulating Spp1 and Fos m6A modification in myocardial infarction

2024-05-03

Abstract excerpt

<title>Abstract</title> <p>While m<sup>6</sup>A modification has been reported in myocardial infarction (MI), the detailed mechanism by which METTL3 regulates the progression of the disease has not yet been elucidated, and it remains unclear why m<sup>6</sup>A modification increases after MI. Through MeRIP-seq and extensive bioinformatics analysis, the target genes SPP1 and FOS with the most significant m<sup>6</...

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Literature Corpus work: 2542f88f-8f53-579a-8553-6e935c4323fd
DOI: 10.21203/rs.3.rs-4207910/v1

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