Article

Epigenetic coordination of transcriptional and translational programs in hypoxia

2023-09-17

Abstract excerpt

<h4>ABSTRACT</h4> Adaptation to cellular stresses entails an incompletely understood coordination of transcriptional and post-transcriptional gene expression programs. Here, we quantified hypoxia-dependent transcriptomes, epigenomes, and translatomes in T47D breast cancer cells and H9 human embryonic stem cells. This revealed pervasive changes in transcription start site (TSS) selection associated with nucleosome...

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Literature Corpus work: 2d1531c7-b2ca-595b-8d15-df39359bd7eb
DOI: 10.1101/2023.09.16.558067

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