Article

Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs

2016-11-17

Abstract excerpt

<h4>ABSTRACT</h4> While long intergenic noncoding RNAs (lincRNAs) and mRNAs share similar biogenesis pathways, these transcript classes differ in many regards. LincRNAs are less evolutionarily conserved, less abundant, and more tissue-specific, suggesting that their pre‐ and post-transcriptional regulation is different from that of mRNAs. Here, we perform an in-depth characterization of the features that contribu...

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Literature Corpus work: 7aecfe92-02fc-50c5-a730-4daa9bcc3911
DOI: 10.1101/088484

Open publication

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