Article

Regulation of Chromatin Accessibility by hypoxia and HIF

2022-01-08

Abstract excerpt

Reduced oxygen availability (hypoxia) can act as a signalling cue in physiological processes such as development, but also in pathological conditions such as cancer or ischaemic disease. As such, understanding how cells and organisms respond to hypoxia is of great importance. The family of transcription factors called Hypoxia Inducible Factors (HIFs) coordinate a transcriptional programme required for survival and...

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Literature Corpus work: b328ebc4-d96f-5406-ac2b-37fc361860a0
DOI: 10.1101/2022.01.07.475388

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