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<i>De novo</i> annotation of lncRNA <i>HOTAIR</i> transcripts by long-read RNA capture-seq reveals a differentiation-driven isoform switch

2022-06-17

Abstract excerpt

<h4>Background</h4> LncRNAs are tissue-specific and emerge as important regulators of various biological processes and as disease biomarkers. HOTAIR is a well-established pro-oncogenic lncRNA which has been attributed a variety of functions in cancer and native contexts. However, a lack of an exhaustive, cell type-specific annotation questions whether HOTAIR functions are supported by the expression of multiple...

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Literature Corpus work
0c3ecca0-7ecc-5c5b-b62a-34e1f1ffc2e2
DOI
10.1101/2022.06.17.496514
Open publication

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<i>De novo</i> annotation of lncRNA <i>HOTAIR</i> transcripts by long-read RNA capture-seq reveals a differentiation-driven isoform switchDOI 10.1101/2022.06.17.496514
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