Article

<i>Brucella</i> Peptide Cross-Reactive MHC I Presentation Activates SIINFEKL-Specific TCR Expressing T Cells

2018-04-14

Abstract excerpt

<h4>ABSTRACT</h4> Brucella spp are intracellular pathogenic bacteria remarkable in their ability to escape immune surveillance and therefore inflict a state of chronic disease within the host. To enable further immune response studies, Brucella were engineered to express the well characterized chicken ovalbumin (OVA). Surprisingly, we found that CD8 T cells bearing T cell receptors (TCR) nominally specific for t...

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Literature Corpus work: 2cf3949c-1ee1-5070-82ff-e97bb938b5f6
DOI: 10.1101/301465

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