Article

Acsl4-mediated Lipid Homeostasis Orchestrates Synaptic and Cognitive Plasticity

2026-04-28

Abstract excerpt

<title>Abstract</title> <p>Intellectual disability (ID) affects 1–3% of the population, yet effective therapies remain elusive. Dysregulated lipid metabolism has been implicated in ID, but the underlying mechanisms and translational potential are poorly understood. Here, we identify the lipid-metabolizing enzyme acyl-coenzyme A (CoA) synthetase long-chain family member 4 (Acsl4) as a key regulator of synaptic pla...

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Literature Corpus work: 2ce25ae8-19b3-5592-aa75-cf9c4fb6f878
DOI: 10.21203/rs.3.rs-7437638/v1

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Acsl4-mediated Lipid Homeostasis Orchestrates Synaptic and Cognitive PlasticityDOI 10.21203/rs.3.rs-7437638/v1Read

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