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Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis

2021-12-23

Abstract excerpt

Influenza A virus (IAV) preferentially infects conducting airway and alveolar epithelial cells in the lung. The outcome of these infections is impacted by the host response, including the production of various cytokines, chemokines, and growth factors. Fibroblast growth factor-9 (FGF9) is required for lung development, can display antiviral activity in vitro , and is upregulated in asymptomatic patients during ea...

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Literature Corpus work
2cc79fb4-132c-5a85-8192-caf2e559a232
DOI
10.1101/2021.12.22.473953
Open publication

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Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesisDOI 10.1101/2021.12.22.473953
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