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Article

Interferon induction and function at the mucosal surface

15 Aug 2013

Abstract excerpt

Interferons (IFNs) are produced in response to virus infection and induce an antiviral state in virtually all cell types. In addition to upregulating the transcription of genes that inhibit virus replication, type I (or -α/β) IFNs also act to orchestrate the adaptive immune response to virus infection. Recently a new family of antiviral cytokines, the type III (or -λ) IFNs, has been identified that activate the...

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PMID: 23947345
DOI: 10.1111/imr.12101

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