Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1

26 Jul 2019

Abstract excerpt

Influenza A virus (IAV) is a respiratory pathogen of high importance to public health. Annual epidemics of seasonal IAV infections in humans are a significant public health and economic burden. IAV also causes sporadic pandemics, which can have devastating effects. The main target cells for IAV replication are epithelial cells in the respiratory epithelium. The cellular innate immune responses induced in these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Influenza Virus Research Studies
Share to interferon and immune responses
Share to Respiratory viral infections research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31375585
DOI: 10.1128/jvi.00559-19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1PMID 31375585Read ↗

Comprehensive single cell analysis of pandemic influenza A virus infection in the human airways uncovers cell-type specific host transcriptional signatures relevant for disease progression and pathogenesisSemantic proximity Read ↗

Comprehensive single cell analysis of pandemic influenza A virus infection in the human airways uncovers cell-type specific host transcriptional signatures relevant for disease progression and pathogenesisSemantic proximity Read ↗

Modulation of Influenza A virus NS1 expression reveals prioritization of host response antagonism at single-cell resolutionSemantic proximity Read ↗

In VivoProfiling of Individual Multiciliated Cells during Acute Influenza A Virus InfectionSemantic proximity Read ↗

Induction of innate immunity and its perturbation by influenza virusesSemantic proximity Read ↗

Influenza A virus interactions with macrophages: Lessons from epithelial cellsSemantic proximity Read ↗

Human nasal and lung tissues infected <i>ex vivo</i> with SARS-CoV-2 provide insights into differential tissue-specific and virus-specific innate immune responses in the upper and lower respiratory tractSemantic proximity Read ↗

Interferon induction and function at the mucosal surfaceSemantic proximity Read ↗

Type I and Type III IFN Restrict SARS-CoV-2 Infection of Human Airway Epithelial CulturesSemantic proximity Read ↗

SARS-CoV-2 Triggers an MDA-5-Dependent Interferon Response Which Is Unable To Control Replication in Lung Epithelial CellsSemantic proximity Read ↗

Transcriptomic comparison of primary human lung cells with lung tissue samples and the human A549 lung cell line highlights cell type specific responses during infections with influenza A virusSemantic proximity Read ↗

MAVS is Important for Antiviral Defense Against Influenza A Virus in a Human Respiratory Epithelium ModelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.