Article

Human airway organoids model SARS-CoV-2 high infectiousness and evasion of interferon response

2020-09-09

Abstract excerpt

<title>Abstract</title> <p>SARS-CoV-2 is more infectious and transmissible in humans than SARS-CoV, despite the genetic relatedness and sharing the same cellular receptor. We sought to assess whether human airway organoids can model SARS-CoV-2 infection in the human airway and elucidate the cellular basis underlying its higher transmissibility. We demonstrate that SARS-CoV-2 can establish a productive infection i...

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Literature Corpus work: b708ac3d-bc43-5053-9ca0-134653a4f307
DOI: 10.21203/rs.3.rs-67556/v1

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