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Article

The MHC class II transactivator affects local and systemic immune responses in an α-synuclein seeded rat model for Parkinson’s disease

2023-03-17

Abstract excerpt

<title>Abstract</title> <p>Parkinson’s disease (PD) is characterized by intraneuronal inclusions of alpha-synuclein (α-Syn), neurodegeneration and a strong neuroinflammatory component. Studies have shown that genetic variants affecting quantity and quality of major histocompatibility complex II (MHCII) have implications in PD susceptibility and that PD patients have α-Syn specific T lymphocytes in circulation. Th...

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Literature Corpus work
2c995c10-9890-534f-902a-c79d3b01be6e
DOI
10.21203/rs.3.rs-2660160/v1
Open publication

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The MHC class II transactivator affects local and systemic immune responses in an α-synuclein seeded rat model for Parkinson’s diseaseDOI 10.21203/rs.3.rs-2660160/v1
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