Article

IGF2-reprogrammed macrophages ameliorate the inflammatory response and protects against the neurodegenerative and neuroinflammatory process in Parkinson`s disease models.

2024-04-03

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the <italic>Substantia Nigra</italic>, which causes motor deficits. The most common histopathological feature of PD is the presence of α-synuclein (α-syn) misfolding protein and neurotoxic accumulations which leads to neuronal loss. Additionally, the inf...

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Literature Corpus work: 912f52f1-7c89-5974-b216-2ea35bfd49b8
DOI: 10.21203/rs.3.rs-4144998/v1

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