Article

Sex-dimorphic neuroprotective effect of CD163 in an α-synuclein mouse model of Parkinson’s disease

2022-10-18

Abstract excerpt

<h4>ABSTRACT</h4> Alpha-synuclein (α-syn) aggregation and immune activation represent hallmark pathological events in Parkinson’s disease (PD). The PD-associated immune response encompasses both brain and peripheral immune cells, although little is known about the immune proteins relevant for such response. We propose that the upregulation of CD163 observed in blood monocytes and in the responsive microglia in th...

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Literature Corpus work: cc71c7ee-ced7-54b5-95b6-2b25081cb852
DOI: 10.1101/2022.10.17.512526

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