Article

Inhibition of neutrophil degranulation by Nexinhib20 delays the development of radiation-induced pulmonary fibrosis

2025-10-23

Abstract excerpt

Despite advances in radiation delivery techniques that enhance tumour targeting and minimise collateral exposure, healthy tissues remain susceptible to radiation-induced fibrosis, a chronic and progressive condition that can severely compromise patient quality of life. Therapeutic options to prevent or treat radiation-induced fibrosis remain limited. Recent work has shown that neutrophils infiltrating healthy lung...

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Literature Corpus work: 2c476e93-e7e3-587f-a7ae-4eb26000cb60
DOI: 10.1101/2025.10.22.684057

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