Article

Improving SBRT by re-wiring immunosuppressive neutrophils in murine pancreatic ductal adenocarcinoma

2025-01-14

Abstract excerpt

Radiation is used to treat pancreatic ductal adenocarcinoma (PDAC) in the locally-advanced setting. Stereotactic body radiation therapy (SBRT), in particular, has shown improved outcomes against conventional RT in a number of clinical trials. One key cell type involved in the response to RT are neutrophils. These innate immune cells are the first responders to tissue damage and infiltrate irradiated tumors in high...

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Literature Corpus work: 3f67d141-9385-5e74-af63-604602ae86b3
DOI: 10.1101/2025.01.10.632412

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