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Article

Identification of molecular signatures involved in radiation-induced lung fibrosis

7 Nov 2018

Abstract excerpt

In radiotherapy, radiation (IR)-induced lung fibrosis has severe and dose-limiting side effects. To elucidate the molecular effects of IR fibrosis, we examined the fibrosis process in irradiated mouse lung tissues. High focal IR (90 Gy) was exposed to a 3-mm volume of the left lung in C57BL6 mice. In the diffused irradiation, 20 Gy dose delivered with a 7-mm collimator almost covered the entire left lung....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30406363
DOI: 10.1007/s00109-018-1715-9

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